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SUMMER INTERN - R&D Process Development and Technology

Location: 

NC-Clayton, US

Contract Type: 
Area:  Research & Development
Req Id:  117587

For more than 75 years, Grifols has worked to improve the health and well-being of people around the world. We are a global healthcare company that produces essential plasma-derived medicines for patients and provides hospitals and healthcare professionals with the tools, information and services they need to deliver expert medical care.,

The proposed project will evaluate the design space of a developmental protein purification process with the goal of developing sufficient robustness for transfer into commercial scale production.  Studies will focus on the effects of various parameters (e.g. pH and protein concentration) on the recovery of specific activity as well as impurity levels to determine optimum operating ranges.
Process steps to be evaluated include suspension of protein paste, protein purification by precipitation/filtration and by ion exchange chromatography, and preparation of bulk protein samples by ultrafiltration, diafiltration, and formulation.  Duties also include analysis of results potentially including the use of statistical software.

 

Requirements:
Candidate must be currently enrolled in 4 year degree program pursuing Bachelor's degree in Biochemistry, Chemistry, Engineering or related field as rising junior or senior, can also be current Master's or PhD student.  Ideal candidate has an interest and general knowledge of unit operations associated protein purification. Computer skills would include Microsoft Office.  Knowledge of statistical design of experiments and/or statistical software is a plus.


Must currently have GPA of 3.0 or higher

Location: NORTH AMERICA : USA : NC-Clayton:USNC0002 - Clayton 

 

Learn more about Grifols