Manufacturing Purification Process Technician
Dublin, IE
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Would you like to join an international team working to improve the future of healthcare? Do you want to enhance the lives of millions of people? Grifols is a global healthcare company that since 1909 has been working to improve the health and well-being of people around the world. We are leaders in plasma-derived medicines and transfusion medicine and develop, produce and market innovative medicines, solutions and services in more than 110 countries and regions. |
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At Grifols, we believe that diversity adds value to our business, our teams, and our culture. We are committed to equal employment opportunities that foster an inclusive environment.
Position Summary:
We are seeking a detail-oriented and skilled Purification Technician to join our manufacturing team. This role is integral to our production process and involves working through a series of rotations designed to develop expertise in equipment preparation, warehouse management, pasteurisation, and albumin purification. The successful candidate will ensure that all processes meet current good manufacturing practices (cGMP), safety standards, and regulatory requirements while contributing to production efficiency and quality.
Accepting applications for future openings
What will you do?
Equipment Preparation
Cleaning & CIP/SIP Procedures:
- Perform Cleaning-In-Place (CIP) operations on mobile tanks, reactors, and hoses within the purification area.
- Conduct Steam-In-Place (SIP) procedures on clean bulk tanks.
Daily Checks & Equipment Setup:
- Execute daily inspections of analytical equipment and room pressures.
- Perform filter integrity testing to ensure proper function.
Equipment & Parts Handling:
- Set up clarification filters required for the purification process.
- Conduct manual cleaning and verification sampling of small parts.
Additional Tasks:
- Operate autoclave runs and part washer runs.
- Assemble and prepare equipment kits for upcoming purification batches.
Clean Warehouse and Dispensary
Compliance & Safety:
- Adhere strictly to departmental, corporate, industrial, health & safety, and regulatory requirements.
- Maintain a safe and clean work environment in accordance with cGMP and standard operating procedures.
Inventory Management:
- Perform regular stock checks of all materials.
- Transfer materials from non-classified areas to Grade C/D areas as required.
Material Dispensing & Documentation:
- Dispense materials needed for production batches and ensure timely replenishment.
- Maintain accurate company documentation and material reconciliation records.
Pasteurisation
Pasteurisation Process:
- Conduct pasteurisation cycles for filled albumin bags.
- Clean pasteuriser baths to maintain operational efficiency.
Post-Pasteurisation Handling:
- Transfer pasteurised bags to designated drying and caging areas.
- Coordinate handover of pasteurised bags to the warehouse team for incubation.
Albumin Purification
Product Processing:
- Suspend Fraction V paste and adjust pH of the product as part of the purification process.
- Clarify the product to remove impurities.
Filtration & Concentration:
- Set up ultrafilters for diafiltration and concentration.
- Perform sterile filtration of formulated products.
Buffer & Stabilizer Preparation:
Make up buffers and stabilizers, ensuring proper formulation with adjusted protein concentration, sodium levels, and stabilizer content.
Advanced Operations:
- Execute heat shock procedures and perform CIP on ultrafilters.
- Conduct aseptic sampling and analytical testing (pH, conductivity, refractometer measurements, osmolality, turbidity) on albumin samples.
Production Management:
- Work independently to maintain production targets, manage multiple priorities, and adjust for production interventions as needed.
- Utilize MRP systems for batch-specific transactions and documentation.
General Responsibilities:
- Consistently meet planning targets and supply chain requirements.
- Make timely decisions specific to your area of work.
- Perform other related duties as assigned.in purification, process engineering, or related fields, is an asset.
What You'll Bring?
Technical Skills
- Familiarity with cGMP guidelines, standard operating procedures, and regulatory requirements in manufacturing.
- Ability to operate and troubleshoot equipment such as autoclaves, part washers, pasteurisers, and filtration systems.
- Experience in inventory management and documentation.
Personal Attributes:
- Strong attention to detail and commitment to quality.
- Ability to work independently and collaboratively in a fast-paced, dynamic environment.
- Excellent problem-solving skills and the capacity to manage multiple tasks and changing priorities.
Phsyical Requirements:
- Ability to stand for long periods, lift materials, and work in various production and warehouse environments.
- Flexibility to work rotating shifts and adhere to production schedules.
Location: EMEA : Irlanda : Dublin:[[cust_building]]